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Hämoblastosen - Akute Leukämien - Akute myeloische Leukämie (AML) -
Weiterführende Informationen

Akute myeloische Leukämie (AML)

Studien und weitere Informationen

 

www.kompetenznetz-leukaemie.de (Studiengruppen, alle Studien)

 

Studien-Allianz Leukämie (SAL); SAL-Studienzentrale: Med. Klinik und Poliklinik I, Universitätsklinikum Dresden,  Fetscherstr. 74, 01307 Dresden; Tel. (03 51)4 58- 3273, Fax 43 67, E-Mail: sal@uniklinikum-dresden.de

 

Teilnahme am AML-Register: Der SAL-Verbund verfügt über eine Infrastruktur aus Dokumentation, Datenmanagement, medizinischer Beratung, zentraler morphologischer, zytogenetischer und molekularer Diagnostik und Studienmaterialdatenbank, die relevante Ergebnisse klinischer und translationaler Forschung ermöglicht.

 

Literatur

 

  • Bumett AK et al: A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment. Cancer 2007; 109: 1114–24

  • Döhner H et al: Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood 2010; 115: 453–74

  • Hegenbart U et al: Treatment for acute myelogenous leukemia by low-dose, total-body, irradiation-based conditioning and hematopoietic cell transplantation from related and unrelated donors. J Clin Oncol 2006; 24: 444–53

  • Krug U et al:  Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: A web-based application for prediction of outcomes. Lancet 2010; 376: 2000-2008

  • Rollig C, et al: Long-term prognosis of acute myeloid leukemia according to the new genetic risk classification of the European LeukemiaNet recommendations: evaluation of the proposed reporting system. J Clin Oncol 2011; 29: 2758-65

  • Schaich M et al: Cytarabine dose of 36 g/m(2) compared with 12 g/m(2) within first consolidation in acute myeloid leukemia: results of patients enrolled onto the prospective randomized AML96 study. J Clin Oncol 2011; 29: 2696-702

  • Stirewalt DL et al: Size of FLT3 internal tandem duplication has prognostic significance in patients with acute myeloid leukemia. Blood 2006; 107: 3724-6

  • Vardiman JW et al: The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 2009; 114: 937–51